Mouse CD2 Alexa Fluor™ Plus 488-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF2828AFP488
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot, Flow Cytometry, CyTOF-ready
Label
Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)
Antibody Source
Polyclonal Goat IgG
Product Specifications
Specificity
Detects mouse CD2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human CD2 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Mouse CD2 Alexa Fluor™ Plus 488-conjugated Antibody
Application
Recommended Usage
CyTOF-ready
Optimal dilution of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilution of this antibody should be experimentally determined.
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Background: CD2
Mouse CD2, also known as LFA-2 and LFA-3 Receptor, is a 55‑66 kDa, variably glycosylated type I transmembrane (TM) protein belonging to the CD2 receptor subset of the Ig superfamily. It is synthesized as a 344 amino acid (aa) precursor that contains a 22 aa signal sequence, a 181 aa extracellular domain (ECD), a 26 aa transmembrane segment, and a proline rich (20%) 115 aa cytoplasmic region. CD2 is found on T and NK cells and binds CD48 in rodents and CD58 in humans. The ECD of mouse CD2 shares 73%, 50% and 44% aa identity with the CD2 ECD in rat, human and equine, respectively.
Alternate Names
CD2, LFA-2, T11
Gene Symbol
CD2
UniProt
Additional CD2 Products
Product Specific Notices for Mouse CD2 Alexa Fluor™ Plus 488-conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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