Mouse BMP-15/GDF-9B Alexa Fluor™ Plus 647-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB5917AFP647
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunohistochemistry
Label
Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 582703
Product Specifications
Specificity
Detects mouse BMP‑15/GDF‑9B in direct ELISAs. In this format, no cross-reactivity with recombinant human BMP1.1, 2, 3, 3b, 4, 5, 6, 7, 8, 9, 10, 15, recombinant mouse BMP-3, 3b, 4, 5, 6, 7, 8b, 9, or 10 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications
Application
Recommended Usage
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Background: BMP-15/GDF-9B
Bone morphogenetic protein 15 (BMP-15), also known as GDF-9B, is a member of the TGF-beta superfamily. Mature BMP-15 has three intrachain disulfide bands that form a cysteine-knot fold. It is secreted as a 34 kDa non-disulfide-linked homodimer and as a 37 kDa nondisulfide heterodimer with GDF-9. BMP-15 is a product of oocytes and promotes granulosa cell proliferation and stem cell factor secretion. Mature mouse BMP-15 shares 44% aa sequence identity with mature mouse GDF-9. It also shares 70% and 78% aa sequence identity with human and sheep BMP-15, respectively.
Long Name
Bone Morphogenetic Protein 15
Alternate Names
BMP15, GDF-9B
Gene Symbol
BMP15
UniProt
Additional BMP-15/GDF-9B Products
Product Specific Notices
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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