KIR2DL2/CD158b1 Antibody (RB23818)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-52289
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Flow Cytometry
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG Clone # RB23818
Concentration
1 mg/ml
Product Specifications
Immunogen
This KIR2DL2/CD158b1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human.(Accession#:NP_055034.2)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for KIR2DL2/CD158b1 Antibody (RB23818)
Western Blot:KIR2DL2/CD158b1 Antibody (RB23818)[NBP3-52289]-
KIR2DL2 Antibody (C-Term) western blot analysis in MDA-MB231,Jurkat cell line lysates (35ug/lane).This demonstrates the KIR2DL2 antibody detected the KIR2DL2 protein (arrow).
Flow Cytometry:KIR2DL2/CD158b1 Antibody (RB23818)[NBP3-52289]-
KIR2DL2 Antibody (C-Term) western blot analysis in MDA-MB231,Jurkat cell line lysates (35ug/lane).This demonstrates the KIR2DL2 antibody detected the KIR2DL2 protein (arrow).Applications for KIR2DL2/CD158b1 Antibody (RB23818)
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen and protein A Affinity-purified
Formulation
PBS
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: KIR2DL2/CD158b1
The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.
Long Name
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2
Alternate Names
CD158b1, CL-43, NKAT6
Gene Symbol
KIR2DL2
Additional KIR2DL2/CD158b1 Products
Product Documents for KIR2DL2/CD158b1 Antibody (RB23818)
Product Specific Notices for KIR2DL2/CD158b1 Antibody (RB23818)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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