Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

Janelia Fluor 646

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2548B

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 6 beta 1 Antibodies »

Product Specifications

Immunogen

Chinese Hamster Ovary cell line, CHO-derived Human Integrin  alpha6 beta1 heterodimer
Phe24-Ser1012(Integrin alpha 6) and Gln21-Asp728 (Integrin beta1)
Accession # NP_000201

Specificity

Detects human Integrin  alpha6 beta1 in direct ELISAs. In direct ELISA, less than 1% of cross reactivity with recombinant human (rh) Integrin beta1 and recombinant mouse (rm) Integrin alpha6 is observed. In direct ELISA, no cross-reactivity with rhIntegrin alpha3, beta2, beta3, beta5, beta6, beta7, and rmIntegrin beta1 is observed.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Integrin alpha 6 beta 1 Antibody (2548B) [Janelia Fluor® 646]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 6 beta 1

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.

Alternate Names

CD49f, ITGA6B, VLA-6

Additional Integrin alpha 6 beta 1 Products

Product Documents for Integrin alpha 6 beta 1 Antibody (2548B) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Integrin alpha 6 beta 1 Antibody (2548B) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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