Human ZSCAN21 Alexa Fluor™ Plus 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF8015AFP647

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AF8015AFP647-100UG
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)

Antibody Source

Polyclonal Sheep IgG

View all ZSCAN21 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human ZSCAN21

Specificity

Detects human ZSCAN21 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ZSCAN21

ZSCAN21 (Zinc finger and SCAN domain-containing protein 21; also Zfp-38, NY-REN-21, Zipro1 and Ru49) is a nuclear member of the multi-finger SCAN box protein family. It is expressed in select cell types, including cerebellar granule cells, Schwann cells, cerebral cortical and sympathetic neurons, round spermatids, and cells of the hair follicles plus sebaceous glands. It may have multiple functions, one of which is to initiate transcription of neuronal alpha-synuclein, while a second may be to promote granule cell proliferation. Human ZSCAN21 is 473 amino acids (aa) in length. It contains one SCAN (SREZBP, Ctfin51, AW-1/ ZNF174, and Number 18) domain (aa 45-127) that mediates dimerization, followed by seven consecutive C2H2-type zinc-finger regions (aa 277-466). ZSCAN21 is known to form both noncovalent homodimers and heterodimers with SCAND1. There is one potential isoform variant that shows a 188 aa substitution for aa 263-473. Over aa 139-223, human ZSCAN21 shares 54% aa sequence identity with mouse ZSCAN21.

Long Name

Zinc Finger and SCAN Domain Containing 21

Alternate Names

KOX25, NY-REN-21, ZFP383, Zipro1, ZNF38

Entrez Gene IDs

7589 (Human)

Gene Symbol

ZSCAN21

UniProt

Q9Y5A6

Additional ZSCAN21 Products

Product Documents

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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