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Human Sulfatase Modifying Factor 1/SUMF1 Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF3680AFP488

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AF3680AFP488-100UG

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG

Product Specifications

Specificity

Detects human SUMF1 in direct ELISAs and Western blots. In these formats, approximately 45% cross-reactivity with recombinant mouse SUMF1 is observed and less than 1% cross-reactivity with recombinant human SUMF2 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Background: Sulfatase Modifying Factor 1/SUMF1

Human SUMF-1 (also FGE) is a 42 kDa (341 aa), Ca++-binding member of the sulfatase-modifying factor family. It is a soluble ER lumenal glycoprotein that converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF-1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF-2. Three splice isoforms are known. Mature human SUMF-1 shares 90% aa sequence identity with mouse SUMF-1.

Alternate Names

FGE1

Entrez Gene IDs

285362 (Human); 58911 (Mouse); 362409 (Rat)

Gene Symbol

SUMF1

UniProt

Additional Sulfatase Modifying Factor 1/SUMF1 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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