Human PAK2 Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6849AFP488

Catalog #
Availability
Size / Price
Qty
FAB6849AFP488-100UG
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG3 Clone # 677411

View all PAK2 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human PAK2

Specificity

Detects human PAK2 in direct ELISAs. In direct ELISAs, approximately 5% cross‑reactivity with recombinant human (rh) PAK1 and no cross-reactivity with rhPAK1B, 3, 4, 6, or 7 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Applications for Human PAK2 Alexa Fluor™ Plus 488-conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PAK2

PAK2 (p21-activated kinase-2) is a widely expressed 58-62 kDa cytoplasmic ser/thr kinase of the PAK family, with substrates including ribosomal S6 and histone H4 proteins. The 524 amino acid (aa) human PAK2 contains phosphorylation, acetylation (K38, K128) and myristoylation (G213) sites, a CRIB (cdc42/Rac interactive binding) domain (aa 74-87), a caspase-3 cleavage site after aa 212, and a kinase domain (aa 249-499). Full-length PAK2 stimulates cell growth and motility, while the caspase cleaved PAK2 kinase domain (34 kDa) is involved in cell death. Within the region used as an immunogen, human PAK2 shares 87% aa identity with mouse and rat PAK2. 

Long Name

p21-activated Kinase 2

Alternate Names

gamma-PAK, PAK65, S6/H4 Kinase

Entrez Gene IDs

5062 (Human); 224105 (Mouse); 29432 (Rat)

Gene Symbol

PAK2

UniProt

Q13177

Additional PAK2 Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human PAK2 Alexa Fluor™ Plus 488-conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.