Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)
R&D Systems, part of Bio-Techne | Catalog # PP-N1404-0C
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # N1404
Product Specifications
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)
Application
Recommended Usage
Immunohistochemistry
Immunoprecipitation
Western Blot
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Nurr1/NGFI-B beta/NR4A2
Nurr1 belongs to the nerve growth factor-induced clone B subfamily of nuclear receptor superfamily and is designated NR4A2 in the Unified Nomenclature System for NRs. Nurr1 can function as a ligand-independent transcription factor. Nurr1 also heterodimerizes with retinoid X receptors (RXRs) to function as ligand-regulated transcription factor. Nurr 1 is important for specification of dopaminergic neurons that degenerate in Parkinsons disease. Human and mouse Nurr1 share 99% amino acid sequence homology.
Long Name
Nur-related Factor 1/Nerve Growth Factor Induced B beta/Nuclear Receptor Subfamily 4, Group A, 2
Alternate Names
NGFI-B beta, NOT, NR4A2, TINUR
Gene Symbol
NR4A2
Additional Nurr1/NGFI-B beta/NR4A2 Products
Product Documents for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)
Product Specific Notices for Human Nurr1/NGFI-B beta/NR4A2 MAb (Protein A Purified)
For research use only
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