Human Neurotensin Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB11548AFP488

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FAB11548AFP488-100UG
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 1075611

View all Neurotensin Antibodies »

Product Specifications

Immunogen

Neurotensin containing synthetic peptide

Specificity

Detects a synthetic peptide around aa 135 in Direct ELISA

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications

Application
Recommended Usage

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Neurotensin

Neurotensin is a neuropeptide neurotransmitter expressed in both the central and peripheral nervous systems.  It acts as a neurotransmitter in the central nervous system and as a hormone in the periphery.  This neuropeptide has many roles in the body such as:  temperature regulation, feeding, analgesia, ethanol sensitivity, psychosis, substance use, and pain. Neurotensin may also play an endocrine or paracrine role in the regulation of fat metabolism.  It is expressed in neuronal synaptic vesicles in the CNS and in the periphery is expressed in the GI tract and in neuroendocrine cells.

References

  1. Torruella-Suárez ML, McElligott ZA. Neurotensin in reward processes. Neuropharmacology. 2020 May 1;167:108005. doi: 10.1016/j.neuropharm.2020.108005. Epub 2020 Feb 11. PMID: 32057800; PMCID: PMC7238864. 
  2. Mazella J, Béraud-Dufour S, Devader C, Massa F, Coppola T. Neurotensin and its receptors in the control of glucose homeostasis. Front Endocrinol (Lausanne). 2012 Nov 26;3:143. doi: 10.3389/fendo.2012.00143. PMID: 23230428; PMCID: PMC3515879.

Long Name

Neurotensin/neuromedin N [Cleaved into: Large neuromedin N

Alternate Names

NTS

Entrez Gene IDs

4922 (Human); 280881 (Bovine)

Gene Symbol

NTS

UniProt

P30990 (Human)

Additional Neurotensin Products

Product Documents

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Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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