Human/Mouse Otoraplin/OTOR Alexa Fluor® 750-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF3979S
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
Alexa Fluor 750 (Excitation = 749 nm, Emission = 775 nm)
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
E. coli-derived recombinant human Otoraplin/OTOR
Val18-Glu128
Accession # Q9NRC9
Val18-Glu128
Accession # Q9NRC9
Specificity
Detects human and mouse Otoraplin/OTOR in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications
Application
Recommended Usage
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: Otoraplin/OTOR
Otoraplin (OTOR), also known as fibrocyte-derived protein (Fdp) and Melanoma inhibitory activity-like (MIAL), is a secreted 16 kDa globular protein that is preferentially expressed in the inner ear by periotic mesenchyme and developing and mature fibrocytes. It is highly homologous to MIA/cartilage-derived retinoic acid‑sensitive protein (CD-RAP), which is a cartilage-specific protein that is also expressed in malignant melanoma cells. The 111 amino acid residue (aa) mature human otoraplin contains one SH3 domain (aa 46‑107) and a Tyr at position 50 that is reportedly sulfated. Otoraplin is reported to play a role in the initiation of periotic mesenchyme chondrogenesis. Mature human Otoraplin shares 91% and 89% aa sequence identity with canine and mouse Otoraplin, respectively.
Alternate Names
MIAL1, OTOR
Gene Symbol
OTOR
UniProt
Additional Otoraplin/OTOR Products
Product Specific Notices
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only
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