Human Lymphotoxin Alexa Fluor™ Plus 680-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1370AFP680

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FAB1370AFP680-100UG
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Key Product Details

Species Reactivity

Human

Applications

Neutralization

Label

Alexa Fluor Plus 680 (Excitation = 687 nm, Emission = 704 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 135125

View all Lymphotoxin Antibodies »

Product Specifications

Specificity

Recognizes human Lymphotoxin alpha chains in alpha

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications

Application
Recommended Usage

Neutralization

Optimal dilution of this antibody should be experimentally determined.

Background: Lymphotoxin

Lymphotoxin alpha, also known as tumor necrosis factor (TNF) beta, and Lymphotoxin beta are members of the TNF superfamily and have been designated TNFSF1 and TNFSF3, respectively. Secreted Lymphotoxin alpha forms a homotrimer (TNF­beta) and heterotrimeric complexes with the type II membrane protein, Lymphotoxin beta (either alpha2 beta1or alpha1 beta2 timers). These trimers serve as ligands for Lymphotoxin beta receptor, TNF RI and TNF RII and play a role in the development and maturation of the immune system.

References

  1. Matthews, N. and M. L. Neale (1987) in Lymphokines and Interferons, A Practical Approach.
  2. Clemens, M. J. et al. (eds): IRL Press. 221.

Alternate Names

LT, Lymphotoxin alpha, tnfb, TNFSF1, TNLG1E

Entrez Gene IDs

4049 (Human); 16992 (Mouse); 102138497 (Cynomolgus Monkey)

Gene Symbol

LTA

Additional Lymphotoxin Products

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Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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