Human Integrin beta6 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB4155A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2B Clone # 437211
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Integrin alphaV beta6
Phe31-Val992 (Integrin alphaV) and Gly22-Asn707 (Integrin beta6)
Accession # P18564 (Integrin beta6)
Phe31-Val992 (Integrin alphaV) and Gly22-Asn707 (Integrin beta6)
Accession # P18564 (Integrin beta6)
Specificity
Detects human Integrin beta6 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Human Integrin beta6 APC-conjugated Antibody
Detection of Integrin beta6 in HT‑29 Human Cell Line by Flow Cytometry.
HT-29 human colon adenocarcinoma cell line was stained with Mouse Anti-Human Integrin beta6 APC-conjugated Monoclonal Antibody (Catalog # FAB4155A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human Integrin beta6 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: HT‑29 human colon adenocarcinoma cell line
Sample: HT‑29 human colon adenocarcinoma cell line
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra Viewer
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: Integrin beta 6
Integrin beta6 (ITG beta6) is a 95 kDa member of the Integrin beta family. It forms noncovalent heterodimers with Integrin alphaV and appears on epithelia following injury or inflammation. It activates TGF-beta and assists keratinocyte migration. Human Integrin beta6 is a type I transmembrane glycoprotein that is 767 amino acids (aa) in length. It contains a 688 aa extracellular domain (ECD) (aa 22-709) that incorporates a 241 aa VWF-A domain. Over aa 22-707, human integrin beta6 ECD shares 90% and 93% aa sequence identity with mouse and pig integrin beta6 ECD, respectively.
Alternate Names
ITGB6
Gene Symbol
ITGB6
UniProt
Additional Integrin beta 6 Products
Product Documents for Human Integrin beta6 APC-conjugated Antibody
Product Specific Notices for Human Integrin beta6 APC-conjugated Antibody
For research use only
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