Human IL-6R alpha (Research Grade Sarilumab Biosimilar) Alexa Fluor® 350-conjugated Antibody

Name: Human IL-6R alpha (Research Grade Sarilumab Biosimilar) Alexa Fluor® 350-conjugated Antibody
Brand: R&D Systems
SKU: FAB10346U

R&D Systems, Inc. a Bio-Techne Brand

Catalog # FAB10346U

Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody For Research Use Only

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Key Product Details

Species Reactivity:	Human
Immunogen:	Human IL-6R alpha
Applications:	Flow Cytometry
Label:	Alexa Fluor 350 (Excitation=346 nm, Emission=442 nm)
Source:	Recombinant Monoclonal Human IgG₁ Clone # Hu137
Specificity:	Detects Human IL-6R alpha based on Sarilumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Sarilumab. This product is for research use only.

View Full Technical Details for Human IL-6R alpha (Research Grade Sarilumab Biosimilar) Alexa Fluor® 350-conjugated Antibody

Applications

	Recommended Concentration	Sample
Flow Cytometry	0.25-1 µg/10⁶ cells	HEK293 Human cell line Transfected with Human IL-6R alpha and eGFP and U937 human histiocytic lymphoma cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Purification	Protein A or G purified from cell culture supernatant
Formulation	Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Background: IL-6R alpha

Sarilumab is a biosimilar directed against human IL-6R alpha.

Item	Value
Long Name	Interleukin 6 Receptor alpha
Entrez Gene IDs	3570 (Human); 16194 (Mouse); 24499 (Rat); 102116430 (Cynomolgus Monkey)
Alternate Names	CD126, IL-6 R alpha, IL-6R alpha, IL-6R-1, IL-6Ra, IL6Q, IL6R, IL6R alpha, IL6RA, IL6RQ, gp80, interleukin 6 receptor

Product Specific Notices

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

Citations for Human IL-6R alpha (Research Grade Sarilumab Biosimilar) Alexa Fluor® 350-conjugated Antibody

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Human IL-6R alpha (Research Grade Sarilumab Biosimilar) Alexa Fluor® 350-conjugated Antibody

R&D Systems, Inc. a Bio-Techne Brand

Key Product Details

Complete Your Research

Applications

Formulation, Preparation and Storage

Plan Your Experiments

Reconstitution Calculator

Background: IL-6R alpha

Product Specific Notices

Citations for Human IL-6R alpha (Research Grade Sarilumab Biosimilar) Alexa Fluor® 350-conjugated Antibody

Product Documents

Product Datasheets

COA

Certificate of Analysis

SDS

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