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Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB9718

Recombinant Monoclonal Antibody For Research Use Only
Discontinued Product
MAB9718 has been discontinued. View all IGF-I R/IGF1R products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Flow Cytometry

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu14

Product Specifications

Immunogen

Human IGF-I R/IGF1R

Specificity

Detects human IGF-I R/IGF1R based on Teprotumumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Teprotumumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Scientific Data Images for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Detection of IGF-I R/IGF1R antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.

Detection of IGF-I R/IGF1R in MCF-7 Human Cell Line by Flow Cytometry.

MCF-7 human cell line was stained with Human Anti-Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Monoclonal Antibody (Catalog # MAB9718, filled histogram) or irrelevant antibody (open histogram) followed by APC-conjugated Anti-Human IgG Secondary Antibody (Catalog # F0135). View our protocol for Staining Membrane-associated Proteins.

Applications for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Application
Recommended Usage

Flow Cytometry

0.25 µg/106 cells
Sample: MCF-7 Human Cell Line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IGF-I R/IGF1R

Teprotumumab is a biosimilar directed against the extracellular domain of IGF-I R/IGF1R. This product constitutes the immunogen used for the anti-Idiotype catalog number MAB9634.

Long Name

Insulin-like Growth Factor I Receptor

Alternate Names

CD221, IGF-1R, IGF-IR, IGF1R, IGFIR

Entrez Gene IDs

3480 (Human)

Gene Symbol

IGF1R

Additional IGF-I R/IGF1R Products

Product Documents for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

For research use only

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