Human HLA-DR PerCP-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB4869C

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

PerCP (Excitation = 482 and 564 nm, Emission = 675 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # L203

View all HLA-DR Antibodies »

Product Specifications

Immunogen

RPMI 8866 human lymphoblastoid cells
Accession # P01903

Specificity

Detects human HLA‑DR.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human HLA-DR PerCP-conjugated Antibody

Detection of HLA-DR antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

Detection of HLA-DR in Human Blood Lymphocytes by Flow Cytometry.

Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human HLA-DR PerCP-conjugated Monoclonal Antibody (Catalog # FAB4869C) or (B) isotype control antibody (Catalog # IC002C) and Mouse anti-Human CD19 CFS-conjugated Monoclonal Antibody (Catalog # FAB4867F). View our protocol for Staining Membrane-associated Proteins.

Applications for Human HLA-DR PerCP-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood lymphocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: HLA-DR

HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4+ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.

Long Name

Major Histocompatibility Complex Class II DR

Alternate Names

HLA-DRA, HLADR, MHC Class II DR

Entrez Gene IDs

3122 (Human)

Gene Symbol

HLA-DRA

UniProt

P01903

Additional HLA-DR Products

Product Documents for Human HLA-DR PerCP-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human HLA-DR PerCP-conjugated Antibody

For research use only

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