Human HLA-DR APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB4869A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # L203
Product Specifications
Immunogen
RPMI 8866 human lymphoblastoid cells
Accession # P01903
Accession # P01903
Specificity
Detects human HLA‑DR.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human HLA-DR APC-conjugated Antibody
Detection of HLA‑DR in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human HLA-DR APC-conjugated Monoclonal Antibody (Catalog # FAB4869A) or (B) isotype control antibody (Catalog # IC002A) Mouse anti-Human CD19 PE-conjugated Monoclonal Antibody (Catalog # FAB4867A). View our protocol for Staining Membrane-associated Proteins.Applications for Human HLA-DR APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
Reviewed Applications
Read 1 review rated 4 using FAB4869A in the following applications:
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Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: HLA-DR
HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4+ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.
Long Name
Major Histocompatibility Complex Class II DR
Alternate Names
HLA-DRA, HLADR, MHC Class II DR
Entrez Gene IDs
3122 (Human)
Gene Symbol
HLA-DRA
UniProt
Additional HLA-DR Products
Product Documents for Human HLA-DR APC-conjugated Antibody
Product Specific Notices for Human HLA-DR APC-conjugated Antibody
For research use only
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