Human CD38 Alexa Fluor® 647-conjugated Antibody

Name: Human CD38 Alexa Fluor® 647-conjugated Antibody
Brand: R&D Systems
SKU: FAB2404R

R&D Systems, part of Bio-Techne | Catalog # FAB2404R

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Product Datasheet / COA / SDS

Discontinued Product

FAB2404R has been discontinued. View all CD38 products.

Key Product Details

Species Reactivity:	Human
Immunogen:	NS0 mouse myeloma cell line transfected with human CD38 Met1-Ile300 Accession # P28907
Applications:	Flow Cytometry
Label:	Alexa Fluor 647 (Excitation=650 nm, Emission=668 nm)
Source:	Monoclonal Mouse IgG_2A Clone # 240742
Specificity:	Detects human CD38.

View Full Technical Details for Human CD38 Alexa Fluor® 647-conjugated Antibody

Technical Data
Citations / Reviews

Applications for Human CD38 Alexa Fluor® 647-conjugated Antibody

	Recommended Concentration	Sample
Flow Cytometry	0.25-1 µg/10⁶ cells	Human whole blood lymphocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Scientific Data Examples for Human CD38 Alexa Fluor® 647-conjugated Antibody

	Flow Cytometry Detection of CD38 in PBMC treated with 5 µg/mL PHA for 5 days by Flow Cytometry PBMC treated with 5 µg/mL PHA for 5 days were stained with Mouse Anti-Human CD3 epsilon APC‑conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Mouse Anti-Human CD38 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB2404R) or (B) isotype control antibody (Catalog # IC003R). View our protocol for Staining Membrane-associated Proteins.

Formulation, Preparation and Storage

Purification	Protein A or G purified from hybridoma culture supernatant
Formulation	Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CD38

CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)⁺ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP⁺, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5).

Item	Value
References	Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249. Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811. Sun, L. et al. (1999) J. Cell Biol. 146:1161. Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209. Kato, I. et al. (1995) J. Biol. Chem. 270:30045.
Long Name	Cluster of Differentiation 38
Entrez Gene IDs	952 (Human); 12494 (Mouse); 25668 (Rat); 102126394 (Cynomolgus Monkey)
Alternate Names	2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20), 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl Cyclase, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADPRC 1, ADPRC1, CD38, CD38 antigen, CD38 antigen (p45), CD38 molecule, CD_antigen: CD38, Cyclic ADP-ribose Hydrolase, Cyclic ADP-ribose hydrolase 1, EC 2.4.99.20, EC 3.2.2.6, EC:3.2.2.6, NAD(+) nucleosidase, T10, cADPr hydrolase 1, cluster of differentiation 38

Product Specific Notices for Human CD38 Alexa Fluor® 647-conjugated Antibody

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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Human CD38 Alexa Fluor® 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB2404R

Key Product Details

Applications for Human CD38 Alexa Fluor® 647-conjugated Antibody

Scientific Data Examples for Human CD38 Alexa Fluor® 647-conjugated Antibody

Flow Cytometry

Formulation, Preparation and Storage

Plan Your Experiments

Reconstitution Calculator

Background: CD38

Product Specific Notices for Human CD38 Alexa Fluor® 647-conjugated Antibody

Customer Reviews for Human CD38 Alexa Fluor® 647-conjugated Antibody

Product Documents for Human CD38 Alexa Fluor® 647-conjugated Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

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