Human CD300b/LMIR5 Alexa Fluor™ Plus 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF2879AFP647

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AF2879AFP647-100UG
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, CyTOF-ready

Label

Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)

Antibody Source

Polyclonal Goat IgG

View all CD300b/LMIR5 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CD300b/LMIR5

Specificity

Detects human CD300b/LMIR5 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human LMIR2 and recombinant mouse LMIR5 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications

Application
Recommended Usage

CyTOF-ready

Optimal dilution of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CD300b/LMIR5

CD300b, also known as LMIR5, CLM7 (CMRF-35-like Molecule 7) and TREM5 (Triggering Receptor Expressed on Myeloid cells 5) belongs to a multigene family whose members are closely mapped to a region of human chromosome 17 and mouse chromosome 11. These genes encode type I membrane proteins with a single extracellular Ig-like domain and the proteins are expressed widely in leukocytes. LMIR/CD300 family proteins are immunoregulatory signaling molecules that either have cytoplasmic ITIM motifs or can interact with ITAM motif-bearing molecules through a characteristic transmembrane domain containing positively charged amino acid residues. CD300b/LMIR5 is an ITAM adaptor-associated receptor with a short cytoplasmic region. Human and mouse CD300b/LMIR5 share approximately 45% amino acid sequence identity.

Long Name

Leukocyte Mono Ig-like Receptor 5

Alternate Names

CD300b, CD300LB, CLM7, Gm253, LMIR5, TREM-5

Entrez Gene IDs

124599 (Human); 217304 (Mouse)

Gene Symbol

CD300LB

UniProt

NP_777552

Additional CD300b/LMIR5 Products

Product Documents

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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