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Human CCR2 PE‑conjugated Antibody

Bio-Techne includes R&D Systems | Catalog # FAB151P

Clone 48607 was used by HLDA to establish CD designation

Key Product Details

Species Reactivity



Flow Cytometry


Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 48607

Product Summary for Human CCR2 PE‑conjugated Antibody


NS0 mouse myeloma cell line transfected with human CCR2
Accession # NP_001116868


Detects human CCR-2 transfectants but not the parental cell line or CCR-5 transfectants.







Scientific Data Images for Human CCR2 PE‑conjugated Antibody

Detection of CCR2 antibody in Human PBMCs antibody by Flow Cytometry.

Detection of CCR2 in Human PBMCs by Flow Cytometry.

Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human CCR2 PE-conjugated Monoclonal Antibody (Catalog # FAB151P) or (B) Mouse IgG2BPhycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.
Detection of Human CCR2 by Flow Cytometry

Detection of Human CCR2 by Flow Cytometry

Monocyte differentiation stages in the BM.Monocyte differentiation stages were characterized by CD45, CD34, CD33 and CD14 expression. HLA-DR and CCR2 expression were measured in each stage and expressed as the number of sites per cell. a/ example of FACs analysis for monocyte differentiation (red: myelo/monoblasts, blue: promonocytes, green: monocytes), and the HLA-DR and CCR2 expression levels in each stage (patient 31, see S1 Table); b/ individual values for HLA-DR expression (n = 10); c/ individual values for CCR2 expression (n = 10 for myelo/monoblasts, n = 11 for other cell populations). Wilcoxon comparisons. Image collected and cropped by CiteAb from the following publication (, licensed under a CC-BY license. Not internally tested by R&D Systems.

Applications for Human CCR2 PE‑conjugated Antibody

Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood mononuclear cells (PBMCs)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 6 reviews rated 4.3 using FAB151P in the following applications:

Published Applications

Read 35 publications using FAB151P in the following applications:

Formulation, Preparation, and Storage


Protein A or G purified from ascites


Supplied in a saline solution containing BSA and Sodium Azide.


The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CCR2

CCR2 is a G-protein linked seven transmembrane domain spanning chemokine receptor that preferentially binds monocyte chemoattractant proteins-1 and -3 (MCP-1 and MCP-3). Two isoforms of this receptor (CCR2A and CCR2B) are expressed on cell surfaces as a result of alternate splicing from the same gene. These two CCR2 variants differ only at their intracellular carboxyl terminals, with the CCR2A form possessing 14 additional amino acids. This may provide a mechanism by which cells responding to similar extracellular ligands can activate different intracellular second messengers. Cells that respond to the action of MCP-1 and therefore are likely to express CCR2 receptors, include monocytes, T cells, NK cells, basophils, mast cells and dendritic cells. A recent report suggests that B cells may also express CCR2 receptors. The recognition that a variety of chemokine receptors, including CCR2, can serve as HIV fusion co-factors and as facilitators of T cell recruitment during inflammation makes chemokine receptor monitoring an important exercise in elucidating the HIV infection process and the regulation of inflammatory reactions.

Alternate Names

CC-CKR-2, CCR2, CCR2B, CD192, CKR2, CKR2A, CMKBR2, FLJ78302, MCP-1-R

Entrez Gene IDs

729230 (Human); 12772 (Mouse); 60463 (Rat)

Gene Symbol



Additional CCR2 Products

Product Documents for Human CCR2 PE‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CCR2 PE‑conjugated Antibody

For research use only