Human CCL3/MIP-1 alpha Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human |
Immunogen: |
E. coli-derived recombinant human CCL3/MIP-1 alpha Ala27-Ala92 Accession # P10147 |
Applications: | Block/Neutralize, ELISA Capture, Immunohistochemistry, Western Blot |
Label: | Unconjugated |
Source: | Polyclonal Goat IgG |
Specificity: |
Detects human CCL3/MIP‑1 alpha in ELISAs and Western blots. In sandwich immunoassays, less than 0.05% cross-reactivity with recombinant human (rh) MIP-1 beta, rhMIP-1δ, rhMIP-3 alpha, rhMIP-3 beta, and recombinant mouse (rm) MIP-1 alpha is observed. Neutralizes the biological activity of recombinant human CCL3/MIP‑1 alpha. In the chemotaxis assay this antibody will also partially neutralize the biological activity of rhMIP-1 beta at a 20 fold higher IgG concentration. It will not neutralize the biological activity of rmMIP-1 beta or rmMIP-1 alpha. |
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Citations for Human CCL3/MIP-1 alpha Antibody (12)
Citations are publications that use Bio-Techne products. Selected citations for Human CCL3/MIP-1 alpha Antibody include:
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Species: Human
Sample Types: Whole Cells
Applications: NeutralizationT Kodama et al. (2020), CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways Lab. Invest., 0(0).
PMID: 32457351 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryT Leng et al. (2019), TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions Cell Rep, 28(12):3077-3091.e5.
PMID: 31533032 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationWalker W et al. (2015), Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers. J Virol, 89(10):5502-14.
PMID: 25740989 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA DevelopmentWu W et al. (2009), Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J. Immunol., 183(9):5799-806.
PMID: 19812208 -
Species: Human
Sample Types: Urine
Applications: Antibody Array DevelopmentHu H et al. (2009), Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation, 87(12):1814-20.
PMID: 19543058 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: Luminex DevelopmentBiancotto A et al. (2008), Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res. Hum. Retroviruses, 24(3):453-62.
PMID: 18327985 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: Luminex DevelopmentBiancotto A et al. (2007), Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood, 109(10):4272-9.
PMID: 17289812 -
Species: Human
Sample Types: Serum
Applications: Luminex DevelopmentPfleger C et al. (2007), Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J. Immunol. Methods, 329(1):214-8.
PMID: 17964594 -
Species: Human
Sample Types: Plasma
Applications: ELISA DevelopmentQui H et al. (2007), Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin. Chem., 53(11):2010-2.
PMID: 18030696 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA DevelopmentMasih-Khan E et al. (2006), MIP-1alpha (CCL3) is a downstream target of FGFR3 and RAS-MAPK signaling in multiple myeloma. Blood, 108(10):3465-71.
PMID: 16849642 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationTownson JR et al. (2002), Gene copy number regulates the production of the human chemokine CCL3-L1. Eur. J. Immunol., 32(10):3016-26.
PMID: 12355456 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationBinninger-Schinzel D et al. (2002), Simian immunodeficiency viruses with defective nef genes show increased susceptibility to the noncytotoxic antiviral activity of CD8+ lymphocytes. , 294(1):209-21.
PMID: 11886279
There are no citations that match your criteria.
Customer Reviews for Human CCL3/MIP-1 alpha Antibody (2)
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Application: ELISASample Tested: Cell culture supernatantSpecies: HumanVerified Customer | Posted 09/07/2019
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Application: ELISASample Tested: Cell Lysates,RAW 264.7 mouse monocyte/macrophage cell lineSpecies: HumanVerified Customer | Posted 08/10/2019
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