Human 5-HT2C APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB5764A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 496214
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with human 5-HT2C
Accession # P28335
Accession # P28335
Specificity
Detects human 5-HT2C in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human 5-HT2C APC-conjugated Antibody
Detection of 5‑HT2C in HEK293 Human Cell Line Transfected with Human 5-HT2C and eGFP by Flow Cytometry.
HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP was stained with either (A) Mouse Anti-Human 5-HT2C APC-conjugated Monoclonal Antibody (Catalog # FAB5764A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.Applications for Human 5-HT2C APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP
Sample: HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: 5-HT2C
5-HT2C is a 45 kDa 7TM receptor that belongs to the G-protein coupled receptor #1 family. It binds serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5-HT2C ligation regulates mood, appetite, and motivation. 5-HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5-HT2C can be generated by RNA editing. Human 5-HT2C shares 89% aa sequence identity with mouse and rat 5-HT2C.
Long Name
5-Hydroxytryptamine Receptor 2C
Alternate Names
5-HTR2C, 5HT2C, HTR2C, Serotonin Receptor 2C
Gene Symbol
HTR2C
UniProt
Additional 5-HT2C Products
Product Documents for Human 5-HT2C APC-conjugated Antibody
Product Specific Notices for Human 5-HT2C APC-conjugated Antibody
For research use only
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