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GSC2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91970

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NBP1-91970
NBP1-91970-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Chromatin Immunoprecipitation-exo-Seq

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PFSIEHILSSLPERSLPARAACPPQPAGRQSPAKPEEP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GSC2 Antibody - BSA Free

Immunohistochemistry-Paraffin: GSC2 Antibody [NBP1-91970]

Immunohistochemistry-Paraffin: GSC2 Antibody [NBP1-91970]

Immunohistochemistry-Paraffin: GSC2 Antibody [NBP1-91970] Staining of human testis shows strong nuclear positivity in Leydig cells.
GSC2 Antibody - BSA Free Chromatin Immunoprecipitation ChIP: GSC2 Antibody - BSA Free

Chromatin Immunoprecipitation ChIP: GSC2 Antibody - BSA Free

ChIP-Exo-Seq composite graph for Anti-GSC2 tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh's Lab at Cornell University.

Applications for GSC2 Antibody - BSA Free

Application
Recommended Usage

Chromatin Immunoprecipitation-exo-Seq

1-10ug per reaction

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GSC2

Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11.Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacialanomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes areassociated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derivefrom the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved inembryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues,as well as in early human development. (provided by RefSeq)

Alternate Names

goosecoid homeobox 2, goosecoid-like, GSC-2, GSC-L, GSCLhomeobox protein goosecoid-2, Homeobox protein goosecoid-like

Gene Symbol

GSC2

Additional GSC2 Products

Product Documents for GSC2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GSC2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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