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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Rat IgG1 Clone # 721926

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse GITR Ligand/TNFSF18
Thr47-Ser173
Accession # NP_899247

Specificity

Detects mouse GITR Ligand/TNFSF18 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) APRIL, rmBAFF, rmEDA, rmFas Ligand, rmLIGHT, rmOX40 Ligand, rmTNF-alpha, rmTRAIL, rmTRANCE, rmTWEAK, rm4-1BB Ligand, recombinant human (rh) EDA-A2, rhLTa1/b2, rhLTa2/b1, rhVEGI, or rhGITR Ligand is observed. In Western blots, no cross-reactivity with rm4‑1BB, rmEDA, rmLIGHT, rmTRAIL, rhGITR Ligand, rhTNF-alpha, recombinant canine TNF‑ alpha, recombinant guinea pig TNF-alpha, or recombinant porcine TNF-alpha is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for GITR Ligand/TNFSF18 Antibody (721926) [Janelia Fluor® 525]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GITR Ligand/TNFSF18

GITRL is encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq]

Long Name

Glucocorticoid Induced TNF Receptor Family Related Gene Ligand

Alternate Names

AITRL, GITRL, TNFSF18

Gene Symbol

TNFSF18

Additional GITR Ligand/TNFSF18 Products

Product Documents for GITR Ligand/TNFSF18 Antibody (721926) [Janelia Fluor® 525]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GITR Ligand/TNFSF18 Antibody (721926) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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