FGFR5/FGFRL1 Antibody [mFluor Violet 450 SE]
Novus Biologicals, part of Bio-Techne | Catalog # AF2257MFV450
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
mFluor Violet 450 SE (Excitation = 406 nm, Emission = 445 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human FGF R5/FGFRL1
Ala25-Pro378
Accession # Q8N441
Ala25-Pro378
Accession # Q8N441
Specificity
Detects human FGF R5/FGFRL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 65% cross‑reactivity with recombinant mouse (rm) FGF R5 and rmFGF R5 beta is observed and less than 1% cross-reactivity with recombinant human (rh) FGF R1 alpha (IIIb), rhFGF R1 alpha (IIIc), rhFGF R1 beta (IIIb), rhFGF R1 beta (IIIc), rhFGF R2 alpha (IIIb), rhFGF R2 alpha (IIIc), rhFGF R2 beta (IIIb), rhFGF R2 beta (IIIc), rhFGF R3 alpha (IIIb), rhFGF R3 (IIIc), and rhFGF R4 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for FGFR5/FGFRL1 Antibody [mFluor Violet 450 SE]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FGFR5/FGFRL1
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
Long Name
Fibroblast Growth Factor Receptor-like 1
Alternate Names
FGF R5, FGFRL1
Gene Symbol
FGFRL1
Additional FGFR5/FGFRL1 Products
Product Documents for FGFR5/FGFRL1 Antibody [mFluor Violet 450 SE]
Product Specific Notices for FGFR5/FGFRL1 Antibody [mFluor Violet 450 SE]
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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