FGFR4 Antibody (137114) [FITC]
Novus Biologicals, part of Bio-Techne | Catalog # FAB685F
Clone 137114 was used by HLDA to establish CD designation
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
FITC (Excitation = 495 nm, Emission = 519 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 137114
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human FGF R4
Met1-Asp369
Accession # P22455
Met1-Asp369
Accession # P22455
Specificity
Detects human FGF R4 in direct ELISAs and Western blots. In Western blots, this antibody shows no cross-reactivity with any isoform of recombinant human (rh) FGF R1, rhFGF R2, rhFGF R3, recombinant mouse (rm) FGF R2, or rmFGF R3.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for FGFR4 Antibody (137114) [FITC]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FGFR4
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
Long Name
Fibroblast Growth Factor Receptor 4
Alternate Names
CD334, FGF R4
Gene Symbol
FGFR4
Additional FGFR4 Products
Product Documents for FGFR4 Antibody (137114) [FITC]
Product Specific Notices for FGFR4 Antibody (137114) [FITC]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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