EDA-A1/Ectodysplasin A1 Antibody [Biotin]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81908B
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
Biotin
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
EDA-A1 antibody was raised against an 19 amino acid peptide near the center of human EDA-A1. The immunogen is located within amino acids 130 - 180 of EDA-A1. Amino Acid Squence: PDEKPYSEEESRRVRRNKR
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Bovine: (89%)
Specificity
EDA-A1/Ectodysplasin A1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA-A1/Ectodysplasin A1 are known to exist.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications for EDA-A1/Ectodysplasin A1 Antibody [Biotin]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Peptide affinity purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: EDA-A1/Ectodysplasin A1
Ectodysplasin-A1 (EDA-A1) is a type II transmembrane protein belonging to the TNF superfamily. It is one of multiple isoforms encoded by the EDA gene. Human EDA-A1 is a 391 amino acid protein with a predicted molecular mass of 41 kDa. Mouse and rat EDA-A1 share 94% amino acid sequence identity with the human protein. EDA-A1 is expressed by keratinocytes, hair follicles, and sweat glands, where it can be localized to the cell surface or cleaved into a soluble form by Furin. EDA-A1 forms a homotrimeric protein that binds to EDAR and activates NF-kappa B signaling. Mutations in EDA are associated with a group of developmental disorders identified as ectodermal dysplasia type 1.
Alternate Names
EDAA1
Gene Symbol
EDA
Additional EDA-A1/Ectodysplasin A1 Products
Product Documents for EDA-A1/Ectodysplasin A1 Antibody [Biotin]
Product Specific Notices for EDA-A1/Ectodysplasin A1 Antibody [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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