DP1 Antibody (24GB2685)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51599

Novus Biologicals, part of Bio-Techne
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NBP3-51599-100ul
NBP3-51599-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB2685

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DP1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human DP1 (Uniprot: Q14186)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for DP1 Antibody (24GB2685)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DP1

The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 forms heterodimers with a second protein, designated DP-1, forming an

Alternate Names

DP1E2F dimerization partner 1, DRTF1Dp-1, DRTF1-polypeptide 1, E2F-related transcription factor, transcription factor Dp-1

Gene Symbol

TFDP1

Additional DP1 Products

Product Documents for DP1 Antibody (24GB2685)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DP1 Antibody (24GB2685)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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