Dopa Decarboxylase/DDC Antibody (CL2962)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-52076

Recombinant Monoclonal Antibody
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NBP3-52076-100ul
NBP3-52076-25ul
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Conjugate
Catalog #
Unconjugated
NBP3-52464
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Alexa Fluor 350
NBP3-52464AF350
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Alexa Fluor 405
NBP3-52464AF405
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Alexa Fluor 488
NBP3-52464AF488
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Alexa Fluor 532
NBP3-52464AF532
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Alexa Fluor 594
NBP3-52464AF594
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Alexa Fluor 647
NBP3-52464AF647
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Alexa Fluor 700
NBP3-52464AF700
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Alexa Fluor 750
NBP3-52464AF750
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Alexa Fluor Plus 405
NBP3-52464AFP405
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Alexa Fluor Plus 488
NBP3-52464AFP488
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Alexa Fluor Plus 555
NBP3-52464AFP555
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Alexa Fluor Plus 594
NBP3-52464AFP594
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Alexa Fluor Plus 647
NBP3-52464AFP647
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Alexa Fluor Plus 680
NBP3-52464AFP680
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Allophycocyanin
NBP3-52464APC
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Biotin
NBP3-52464B
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CoraFluor 1
NBP3-52464CL1
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DyLight 350
NBP3-52464UV
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DyLight 405
NBP3-52464V
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DyLight 488
NBP3-52464G
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DyLight 550
NBP3-52464R
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DyLight 594
NBP3-52464DL594
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DyLight 650
NBP3-52464C
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DyLight 680
NBP3-52464FR
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DyLight 755
NBP3-52464IR
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FITC
NBP3-52464F
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HRP
NBP3-52464H
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Janelia Fluor 525
NBP3-52464JF525
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Janelia Fluor 549
NBP3-52464JF549
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Janelia Fluor 646
NBP3-52464JF646
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Janelia Fluor 669
NBP3-52464JF669
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mFluor Violet 450 SE
NBP3-52464MFV450
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mFluor Violet 500 SE
NBP3-52464MFV500
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mFluor Violet 610 SE
NBP3-52464MFV610
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PE
NBP3-52464PE
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PerCP
NBP3-52464PCP
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # CL2962

Concentration

1 mg/ml

View all Dopa Decarboxylase/DDC Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P20711, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Dopa Decarboxylase/DDC Antibody (CL2962)

Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of mouse substantia nigra shows strong positivity in dopamine neurons in pars compacta.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of human fallopian tube shows no positivity in glandular cells as expected.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Analysis in human kidney and fallopian tube tissues. Corresponding Dopa Decarboxylase/DDC RNA-seq data are presented for the same tissues.
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Applications for Dopa Decarboxylase/DDC Antibody (CL2962)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dopa Decarboxylase/DDC

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Alternate Names

AADC, DDC

Gene Symbol

DDC

Additional Dopa Decarboxylase/DDC Products

Product Documents for Dopa Decarboxylase/DDC Antibody (CL2962)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Dopa Decarboxylase/DDC Antibody (CL2962)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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