DLL3 Antibody (SC16.15) - Chimeric - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-45128
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat, Cynomolgus Monkey
Applications
ELISA, Flow Cytometry, Functional
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # SC16.15
Format
BSA Free
Concentration
1 mg/ml
Product Specifications
Immunogen
Three strains of mice (Balb/c, CD-1 and FVB) were immunized with recombinant human DLL3-Fc or with human DLL3-His fusion constructs (Uniprot#: Q9NYJ7)
Specificity
This antibody binds human DLL3 in the N-terminal domain
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Applications for DLL3 Antibody (SC16.15) - Chimeric - BSA Free
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Functional
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody can mediate killing of tumor cells expressing DLL3 and facilitate the delivery of cytotoxic agents to live cells, in an vitro cell killing assay. This antibody was capable of killing OV26 cells, an ovarian NET NTX tumor, with a sub-picomolar EC50 (e.g. 0.14 pM).
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Format
BSA Free
Preservative
0.02% Proclin 300
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: DLL3
Long Name
Delta-like 3
Alternate Names
Pudgy, SCDO1
Gene Symbol
DLL3
Additional DLL3 Products
Product Documents for DLL3 Antibody (SC16.15) - Chimeric - BSA Free
Product Specific Notices for DLL3 Antibody (SC16.15) - Chimeric - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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