BMP-2/BMP-7 Heterodimer Antibody (369505) [DyLight 405]
Novus Biologicals, part of Bio-Techne | Catalog # FAB3229E
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
DyLight 405 (Excitation = 400 nm, Emission = 420 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 369505
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human BMP‑2/BMP‑7 Heterodimer
Ala284-Arg396 (BMP-2), Ser293-His431 (BMP-7)
Accession # NP_001191, NP_001710
Ala284-Arg396 (BMP-2), Ser293-His431 (BMP-7)
Accession # NP_001191, NP_001710
Specificity
Detects human BMP‑2/BMP‑7 Heterodimer in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant human (rh) BMP-2 is observed, and no cross-reactivity with rhBMP-4/7, -4, -5, -6, -7, or -8 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for BMP-2/BMP-7 Heterodimer Antibody (369505) [DyLight 405]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: BMP-2/BMP-7 Heterodimer
BMP-7, also known as osteogenic protein 1 (OP-1), and BMP-2 are TGF-beta superfamily cytokines that influence a variety of morphogenic processes, particularly during skeletal and renal development. BMP-2 and BMP-7 are co-expressed in some embryonic tissues and associate into a functional 38 kDa osteogenic dimer. In in vitro osteoblast differentiation assays and in vivo bone formation models, BMP-2/BMP-7 is significantly more potent than either homodimer.
Long Name
Bone Morphogenetic Protein 2/7
Alternate Names
BDA2;BMP2A;Bone morphogenetic protein 2;SSFSC;SSFSC1
Gene Symbol
BMP2
Additional BMP-2/BMP-7 Heterodimer Products
Product Documents for BMP-2/BMP-7 Heterodimer Antibody (369505) [DyLight 405]
Product Specific Notices for BMP-2/BMP-7 Heterodimer Antibody (369505) [DyLight 405]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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