Axl Antibody [ADC] - (Enapotamab Vedotin, Research Grade)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44503
Key Product Details
Species Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional
Label
ADC
Antibody Source
Monoclonal Human IgG1
Concentration
LYOPH mg/ml
Product Specifications
Immunogen
Axl (Uniprot: P30530)
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Theoretical MW
150.63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).
Enapotamab vedotin (previously referred to as HuMax-AXL-ADC or AXL-107-MMAE) is a clinical-stage AXL-specific antibody-drug conjugate that was generated by conjugating a human AXL-specific IgG1 with the microtubule-disrupting agent monomethyl auristatin E (MMAE) via a protease-cleavable
Enapotamab vedotin (previously referred to as HuMax-AXL-ADC or AXL-107-MMAE) is a clinical-stage AXL-specific antibody-drug conjugate that was generated by conjugating a human AXL-specific IgG1 with the microtubule-disrupting agent monomethyl auristatin E (MMAE) via a protease-cleavable
Scientific Data Images for Axl Antibody [ADC] - (Enapotamab Vedotin, Research Grade)
![Hu Axl mAb [ADC] - (Enapotamab Vedotin)](https://resources.bio-techne.com/images/products/nbp3-44503_human-axl-enapotamab-vedotin-mab-flow-cytometry-18220261037434.png "Flow Cytometry: Hu Axl mAb [ADC] - (Enapotamab Vedotin) [NBP3-44503]")
Flow Cytometry: Hu Axl mAb [ADC] - (Enapotamab Vedotin) [NBP3-44503]
Human Axl HEK293 Cell Line were stained with Axl and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC50 is 0.16 ug/mL.Applications for Axl Antibody [ADC] - (Enapotamab Vedotin, Research Grade)
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Functional
Optimal dilutions of this antibody should be experimentally determined.
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra Viewer
Formulation, Preparation, and Storage
Purification
>95%, by HPLC
Reconstitution
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
Formulation
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH mg/ml
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Background: Axl
Long Name
Axl Receptor Tyrosine Kinase
Alternate Names
AI323647, ARK, JTK11, Tyro7, UFO
Additional Axl Products
Product Documents for Axl Antibody [ADC] - (Enapotamab Vedotin, Research Grade)
Product Specific Notices for Axl Antibody [ADC] - (Enapotamab Vedotin, Research Grade)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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