APRIL/TNFSF13 Antibody (Aprily-5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97599

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse (Negative)

Cited:

Human

Applications

Validated:

ELISA, Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # Aprily-5

Format

BSA Free

Concentration

1.0 mg/ml

View all APRIL/TNFSF13 Antibodies »

Product Specifications

Immunogen

Recombinant human APRIL (aa 93-233).

Specificity

Recognizes full-length and cleaved human APRIL.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for APRIL/TNFSF13 Antibody (Aprily-5) - BSA Free

Western Blot: APRIL/TNFSF13 Antibody (Aprily-5)BSA Free [NBP1-97599]

Western Blot: APRIL/TNFSF13 Antibody (Aprily-5)BSA Free [NBP1-97599]

APRIL-TNFSF13-Antibody-Aprily-5-Western-Blot-NBP1-97599-img0002.jpg
Western Blot: APRIL/TNFSF13 Antibody (Aprily-5)BSA Free [NBP1-97599]

Western Blot: APRIL/TNFSF13 Antibody (Aprily-5)BSA Free [NBP1-97599]

Western Blot: APRIL/TNFSF13 Antibody (Aprily-5) [NBP1-97599] - Detection of endogenous human APRIL with MAb to APRIL (human) (Aprily-5). Method: Cell lysate (A) or cell supernatant (B) were run on an SDS-PAGE gel and analyzed with 2ug/ml Aprily-5 by Western blot. Dendritic cells (1), NIH3T3 (2) and NIH3T3 expressing human APRIL (3).

Applications for APRIL/TNFSF13 Antibody (Aprily-5) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APRIL/TNFSF13

TNFSF13 is a proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Long Name

A Proliferation-inducing Ligand

Alternate Names

CD256, TALL2, TNFSF13, TRDL1, ZTNF2

Gene Symbol

TNFSF13

Additional APRIL/TNFSF13 Products

Product Documents for APRIL/TNFSF13 Antibody (Aprily-5) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for APRIL/TNFSF13 Antibody (Aprily-5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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