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5-HT3B Antibody, Novus Biologicals

Bio-Techne includes Novus Biologicals | Catalog # NBP1-51969

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NBP1-51969

Key Product Details

Species Reactivity

Validated:

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Summary for 5-HT3B Antibody

Immunogen

Peptide with sequence C-SNYLQTQDQTDQQE corresponding to internal region (near C-terminus) according to NP_006019.1.

Epitope

C-SNYLQTQDQTDQQE

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for 5-HT3B Antibody

Western Blot: 5-HT3B Antibody [NBP1-51969] - (1ug/ml) staining of Human Cerebral Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for 5-HT3B Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 51 kDa band observed in human brain (cerebral cortex, hippocampus and amygdala) lysates (calculated MW of 50.3 kDa band according to NP_006019.1).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: 5-HT3B

The product of the HT3B belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. (provided by RefSeq)

Long Name

5-Hydroxytryptamine Receptor 3B

Alternate Names

5HT3B, HTR3B

Entrez Gene IDs

9177 (Human)

Gene Symbol

HTR3B

Additional 5-HT3B Products

Product Documents for 5-HT3B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 5-HT3B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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