Skip to main content

Wnt-3a Products

Wnt-3a is a secreted protein that is necessary for proper embryonic development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. It also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells. The post-translational glycosylation and acylation of Wnts are essential for their efficient secretion and biological activity, respectively. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta-catenin levels. As intracellular beta-catenin levels rise, beta-catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes.

72 results for "Wnt-3a" in Products

Back to Search Results
Apply

Search

Wnt-3a Products

Wnt-3a is a secreted protein that is necessary for proper embryonic development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. It also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells. The post-translational glycosylation and acylation of Wnts are essential for their efficient secretion and biological activity, respectively. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta-catenin levels. As intracellular beta-catenin levels rise, beta-catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes.

72 results for "Wnt-3a" in Products

Wnt/β-catenin signaling inhibitor; axin stabilizer

CyTOF-ready, ELISA, Flow, ICC/IF, IHC, WB
ELISA
ELISA, ICC/IF, IHC, WB
Catalog #: IC13242U
ICFlow

Recombinant Monoclonal Antibody.

endo-IWR 1 synthesized to Ancillary Material Grade

WB, CyTOF-ready, ICFlow

Recombinant Monoclonal Antibody.

Wnt pathway inhibitor

Catalog #: 1324-WNP
BA, BA
Catalog #: IC13242N
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC13242T
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC13242G
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC13242S
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC13242V
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC13242R
ICFlow

Recombinant Monoclonal Antibody.

IHC, WB

Recombinant Monoclonal Antibody

Results Per Page
5 10 25 50
/ 3