
TFPI Products
Tissue Factor Pathway Inhibitor (TFPI) is a key regulator of the extrinsic coagulation pathway. It inhibits coagulation through the formation of a quaternary complex with Coagulation Factor X, Coagulation Factor III/Tissue Factor, and Coagulation Factor VII, thereby preventing the activation of Factor X. TFPI also exhibits anti-angiogenic and anti-metastatic effects. It is produced by vascular endothelial cells and circulates as a free molecule, on platelet surfaces, and in complex with LDL and HDL particles. Abnormal TFPI concentrations in the circulation are associated with thrombosis, disseminated intravascular coagulation, and sepsis. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases.
15 results for "TFPI" in Products
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TFPI Products
Tissue Factor Pathway Inhibitor (TFPI) is a key regulator of the extrinsic coagulation pathway. It inhibits coagulation through the formation of a quaternary complex with Coagulation Factor X, Coagulation Factor III/Tissue Factor, and Coagulation Factor VII, thereby preventing the activation of Factor X. TFPI also exhibits anti-angiogenic and anti-metastatic effects. It is produced by vascular endothelial cells and circulates as a free molecule, on platelet surfaces, and in complex with LDL and HDL particles. Abnormal TFPI concentrations in the circulation are associated with thrombosis, disseminated intravascular coagulation, and sepsis. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases.
15 results for "TFPI" in Products
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
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Sensitivity : | 6.7 pg/mL |
Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 32 different protease inhibitor antibodies
Source : | NS0 |
Accession # : | P10646 |
Applications : | Inhibition Activity |
Assay Range : | 15.6 - 1,000 pg/mL |
Applications : | ELISA |
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #374718 |
Applications : | ELISA Capture |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunoprecipitation, Simple Western, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunoprecipitation, Simple Western, Western Blot |
Source : | NS0 |
Accession # : | O54819 |
Applications : | Inhibition Activity |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #374720 |
Applications : | Immunoprecipitation, Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #372311 |
Applications : | Western Blot |
Assay Range : | 62.5 - 4,000 pg/mL |
Applications : | ELISA |