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42 results for "SorLA" in Products

SorLA Products

SorLA (Sorting protein-related receptor containing LDLR class A repeats; also LR11 and SorL1) is a 250 - 330 kDa, monomeric member of the SORL1 family of proteins. It is expressed on the cell surface (10%) and in Golgi/ER membranes (90%) of neurons and vascular smooth muscle cells. SorLA binds apoE-rich lipoproteins plus the 39 kDa RAP. It also acts as an intracellular sorting receptor for APP. In this context, it blocks transport of APP into compartments that exhibit beta-secretase activity, ...

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Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Catalog #: NBP3-51914
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