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208 results for "RIPK1/RIP1" in Products

RIPK1/RIP1 Products

RIPK1 (Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1), also known as RIP1, contains an N-terminal protein kinase domain, a C-terminal death domain, and a unique internal region called the intermediate domain. It is a serine/threonine protein kinase and is constitutively expressed in many tissues. RIPK1 interacts with the cytoplasmic death domain of FAS and TNF receptors, and is an important element in apoptotic processes. RIPK1 has been shown to interact with a number of proteins including TRADD, TRAF1, TRAF2, and TRAF3, to form larger signaling complexes. These complexes, in turn, activate specific signaling cascades, such as NFkB.

Recombinant Monoclonal Antibody

Catalog #: FAB3585AFP680
Catalog #: FAB3585AFP555
Catalog #: FAB3585AFP594
Catalog #: FAB3585AFP488
Catalog #: FAB3585AFP647
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