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R-Spondin 3 Products
R-Spondin 3 (RSPO3; Cristin 1) is a secreted Wnt regulating protein that is critical for development of the placental labyrinthine layer. It is expressed in the roof plate, tail, somites, otic vesicles, cephalic mesoderm, truncus arteriosus, atrioventricular canal of the developing heart, and strongly but transiently in developing limbs. R-Spondins regulate Wnt/β-catenin by competing with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors LRP-6 and Kremen, reducing their DKK-1-mediated internalization. Reports differ on whether R-Spondins bind LRP-6 directly.
13 results for "R-Spondin 3" in Products
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R-Spondin 3 Products
R-Spondin 3 (RSPO3; Cristin 1) is a secreted Wnt regulating protein that is critical for development of the placental labyrinthine layer. It is expressed in the roof plate, tail, somites, otic vesicles, cephalic mesoderm, truncus arteriosus, atrioventricular canal of the developing heart, and strongly but transiently in developing limbs. R-Spondins regulate Wnt/β-catenin by competing with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors LRP-6 and Kremen, reducing their DKK-1-mediated internalization. Reports differ on whether R-Spondins bind LRP-6 directly.
13 results for "R-Spondin 3" in Products
BA
| Source : | CHO |
| Accession # : | Q9BXY4 |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB41201
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #400403 |
| Applications : | Western Blot |
Catalog #:
4120-RS
BA
| Source : | CHO |
| Accession # : | Q2TJ95 |
| Applications : | Bioactivity |
Catalog #:
AF3500
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
AF35001
Neut
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Block/Neutralize |
Catalog #:
10948-RS
BA
| Source : | HEK293 |
| Accession # : | XP_005551811.1 |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 9.38 - 600 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB4120
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #400404 |
| Applications : | Western Blot |
Catalog #:
MAB3500
ELISA
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1028220 |
| Applications : | ELISA |
Catalog #:
MAB35001
ELISA
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1028231 |
| Applications : | ELISA |
