R-Spondin 3 Products
R-Spondin 3 (RSPO3; Cristin 1) is a secreted Wnt regulating protein that is critical for the development of the placental labyrinthine layer. It is expressed in the roof plate, tail, somites, otic vesicles, cephalic mesoderm, truncus arteriosus, atrioventricular canal of the developing heart, and strongly but transiently in developing limbs.
R-Spondins regulate Wnt/β-catenin by competing with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors LRP-6 and Kremen, reducing their DKK-1-mediated internalization. Reports differ on whether R-Spondins bind LRP-6 directly.
Products:
292 results for "R-Spondin 3" in Products
292 results for "R-Spondin 3" in Products
R-Spondin 3 Products
R-Spondin 3 (RSPO3; Cristin 1) is a secreted Wnt regulating protein that is critical for the development of the placental labyrinthine layer. It is expressed in the roof plate, tail, somites, otic vesicles, cephalic mesoderm, truncus arteriosus, atrioventricular canal of the developing heart, and strongly but transiently in developing limbs.
R-Spondins regulate Wnt/β-catenin by competing with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors LRP-6 and Kremen, reducing their DKK-1-mediated internalization. Reports differ on whether R-Spondins bind LRP-6 directly.
Products:
Analyzed by SEC-MALS
| Source: | CHO |
| Accession #: | Q9BXY4 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | Q2TJ95 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | XP_005551811.1 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #400404 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3D5 |
| Applications: | IHC |
![Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) - Azide and BSA Free [NBP2-73949]](https://resources.bio-techne.com/images/products/R-Spondin-3-Antibody-OTI3D5-Azide-and-BSA-Free-Immunohistochemistry-NBP2-73949-img0015.jpg "Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) - Azide and BSA Free [NBP2-73949]")
| Assay Range: | 9.38 - 600 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | Q9BXY4.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Monoclonal Clone #400403 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1028231 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1028220 |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Monoclonal Clone #400403 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3D5 |
| Applications: | IHC |
![Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) [NBP2-45637]](https://resources.bio-techne.com/images/products/R-Spondin-3-Antibody-3D5-Immunohistochemistry-NBP2-45637-img0015.jpg "Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) [NBP2-45637]")
| Source: | CHO |
| Accession #: | Q9BXY4.1 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | Q2TJ95.2 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Monoclonal Clone #400403 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Monoclonal Clone #400403 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #400404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |