PTP1B: Small Molecules and Peptides
Protein tyrosine phosphatase 1B (PTP1B) dephosphorylates tyrosine residues on several proteins including c-Src, beta-catenin, and the receptors for insulin and epidermal growth factor. PTP1B knock-out mice are resistant to high-caloric intake-induced obesity and have exaggerated insulin responses, suggesting that PTP1B may play a role in regulating growth factor responsiveness.
2 results for "PTP1B Small Molecules and Peptides" in Products
2 results for "PTP1B Small Molecules and Peptides" in Products
PTP1B: Small Molecules and Peptides
Protein tyrosine phosphatase 1B (PTP1B) dephosphorylates tyrosine residues on several proteins including c-Src, beta-catenin, and the receptors for insulin and epidermal growth factor. PTP1B knock-out mice are resistant to high-caloric intake-induced obesity and have exaggerated insulin responses, suggesting that PTP1B may play a role in regulating growth factor responsiveness.
Substrate for PTP1B, TC-PTP, SHP-2, and Tyrosine Phosphatase
Competitive PTP1B inhibitor
| Chemical Name: | 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
