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9 results for "PTEN" in Products
PTEN Products
The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
KO, IHC, WB, Flow, CyTOF-ready
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #217702
Applications:
KO, IHC, WB, Flow, CyTOF-ready
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #217702R
Applications:
KO, WB, Flow
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, ICC/IF
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #1042838
Applications:
KO, ICC/IF
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #1042824
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL11722
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #CL11723
Applications:
IHC