PLC-gamma 1: Small Molecules and Peptides
PLC gamma-1 is an intracellular protein that contains two SH2, one SH3, one plekstrin homology (PH), and two catalytic domains. Activated PLC gamma-1 catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to produce the second messengers inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). IP3 mobilizes the release of calcium while DAG activates protein kinase C. PLC gamma-1 is activated by receptor tyrosine kinases in response to growth factors and hormones, and plays an important role in regulating cell proliferation and differentiation.
2 results for "PLC-gamma 1 Small Molecules and Peptides" in Products
2 results for "PLC-gamma 1 Small Molecules and Peptides" in Products
PLC-gamma 1: Small Molecules and Peptides
PLC gamma-1 is an intracellular protein that contains two SH2, one SH3, one plekstrin homology (PH), and two catalytic domains. Activated PLC gamma-1 catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to produce the second messengers inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). IP3 mobilizes the release of calcium while DAG activates protein kinase C. PLC gamma-1 is activated by receptor tyrosine kinases in response to growth factors and hormones, and plays an important role in regulating cell proliferation and differentiation.
Phospholipase C activator
| Chemical Name: | 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Selective PC-PLC inhibitor
| Chemical Name: | O-(Octahydro-4,7-methano-1H-inden-5-yl) carbonopotassium dithioate |
| Purity: | ≥98% (HPLC) |
