5 results for "PHLDA3" in Products
PHLDA3 Products
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow |
| Applications: | WB, ELISA, MA, AP |
![Western Blot: PHLDA3 Overexpression Lysate [NBL1-14369]](https://resources.bio-techne.com/images/products/PHLDA3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14369-img0002.jpg "Western Blot: PHLDA3 Overexpression Lysate [NBL1-14369]")
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human PHLDA3 GST (N-Term) Protein [H00023612-Q01]](https://resources.bio-techne.com/images/products/qc_test-H00023612-Q01-1.jpg "SDS-PAGE: Recombinant Human PHLDA3 GST (N-Term) Protein [H00023612-Q01]")