P2X3/P2RX3: Small Molecules and Peptides
P2RX3 functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Studies suggest that P2RX3 is important for peripheral pain responses. It participates in pathways controlling urinary bladder volume reflexes. Selective antagonists may have therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Products:
3 results for "P2X3/P2RX3 Small Molecules and Peptides" in Products
3 results for "P2X3/P2RX3 Small Molecules and Peptides" in Products
P2X3/P2RX3: Small Molecules and Peptides
P2RX3 functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Studies suggest that P2RX3 is important for peripheral pain responses. It participates in pathways controlling urinary bladder volume reflexes. Selective antagonists may have therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Products:
Potent P2X3 antagonist
| Chemical Name: | 4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonic acid tetrasodium salt |
| Purity: | ≥90% (HPLC) |
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
| Chemical Name: | 5-[[[(3-Phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt |
| Purity: | ≥98% (HPLC) |
Selective P2X3 and P2X2/3 antagonist
| Chemical Name: | 5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
