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NPRA/NPR1 Products
Natriuretic peptide receptor A/guanylate cyclase A (NPRA), also called NPR-1 or GC-A, is a 120 - 140 kDa type I transmembrane glycoprotein that is the primary receptor for natrietic peptides ANP and BNP. Binding of ANP to the extracellular ligand binding domain (aa 54 - 415), plus ATP to the intracellular kinase homology domain (aa 528 - 805) activates a cytoplasmic guanylate cyclase (aa 840 - 1023). NPRA is expressed most highly in kidney, adrenal and adipose tissue. Human NPRA extracellular domain shows 86%, 44% and 34% aa identity with mouse NPRA, human NPRB and human NPRC, respectively.
8 results for "NPRA/NPR1" in Products
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NPRA/NPR1 Products
Natriuretic peptide receptor A/guanylate cyclase A (NPRA), also called NPR-1 or GC-A, is a 120 - 140 kDa type I transmembrane glycoprotein that is the primary receptor for natrietic peptides ANP and BNP. Binding of ANP to the extracellular ligand binding domain (aa 54 - 415), plus ATP to the intracellular kinase homology domain (aa 528 - 805) activates a cytoplasmic guanylate cyclase (aa 840 - 1023). NPRA is expressed most highly in kidney, adrenal and adipose tissue. Human NPRA extracellular domain shows 86%, 44% and 34% aa identity with mouse NPRA, human NPRB and human NPRC, respectively.
8 results for "NPRA/NPR1" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #377029 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #377018 |
| Applications : | Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #488620 |
| Applications : | Immunohistochemistry |
| Source : | NS0 |
| Accession # : | P18293 |
Highly potent and competitive NPRA antagonist
| Purity : | ≥95% (HPLC) |
