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NKp30/NCR3: Proteins and Enzymes
NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
4 results for "NKp30/NCR3 Proteins and Enzymes" in Products
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NKp30/NCR3: Proteins and Enzymes
NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
4 results for "NKp30/NCR3 Proteins and Enzymes" in Products
| Source : | NS0 |
| Accession # : | Q14931.1 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | XP_005553602.1 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | NP_861543.2 |
| Applications : | Bioactivity |
