121 results for "Niemann-Pick Type C1/NPC1" in Products
Niemann-Pick Type C1/NPC1 Products
Niemann-Pick type C1 (NPC1) is a member of a family of genes encoding membrane-bound proteins containing putative sterol sensing domains. The protein regulates cholesterol transport from late endosomes-lysosomes to other intracellular compartments. NPC1 overexpression increases both the rate of trafficking of low density lipoprotein cholesterol to the endoplasmic reticulum and the rate of delivery of endosomal cholesterol to the plasma membrane. NPC disease is an inherited neurovisceral lipid storage disorder of unesterified cholesterol accumulation in lysosomes. It is characterized by progressive neural and liver degeneration, resulting from inactivating mutations in NPC1, in most cases.
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Applications: | WB, IHC, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG1 Monoclonal Clone #1318A |
| Reactivity: | Human, Mouse, Rat, Porcine, Primate, +3 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, B/N, +3 More |
![Western Blot: Niemann-Pick C1 AntibodyBSA Free [NB400-148]](https://resources.bio-techne.com/images/products/Niemann-Pick-C1-Antibody---BSA-Free-Western-Blot-NB400-148-img0015.jpg "Western Blot: Niemann-Pick C1 AntibodyBSA Free [NB400-148]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1318A |
| Applications: | IHC, WB, ICC/IF, KO |
![Western Blot: Niemann-Pick C1 Antibody (1318A) - BSA Free [NBP2-76798]](https://resources.bio-techne.com/images/products/Niemann-Pick-C1-Antibody-1318A-Knockout-Validated-NBP2-76798-img0002.jpg "Western Blot: Niemann-Pick C1 Antibody (1318A) - BSA Free [NBP2-76798]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1318A |
| Applications: | IHC, WB, ICC/IF, KO |
![Western Blot: Niemann-Pick C1 Antibody (1318A)Azide and BSA Free [NBP2-80879]](https://resources.bio-techne.com/images/products/Niemann-Pick-C1-Antibody-1318A-Azide-and-BSA-Free-Western-Blot-NBP2-80879-img0001.jpg "Western Blot: Niemann-Pick C1 Antibody (1318A)Azide and BSA Free [NBP2-80879]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4H2 |
| Applications: | WB, ELISA |
![Western Blot: Niemann-Pick C1 Antibody (4H2) [H00004864-M02]](https://resources.bio-techne.com/images/products/Niemann-Pick-C1-Antibody-4H2-Western-Blot-H00004864-M02-img0003.jpg "Western Blot: Niemann-Pick C1 Antibody (4H2) [H00004864-M02]")
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #24GB620 |
| Applications: | WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Niemann-Pick C1 Antibody [NBP2-54678]](https://resources.bio-techne.com/images/products/Niemann-Pick-C1-Antibody-Immunohistochemistry-Paraffin-NBP2-54678-img0001.jpg "Immunohistochemistry-Paraffin: Niemann-Pick C1 Antibody [NBP2-54678]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Niemann-Pick C1 Antibody [NBP2-26214]](https://resources.bio-techne.com/images/products/Niemann-Pick-C1-Antibody-Western-Blot-NBP2-26214-img0001.jpg "Western Blot: Niemann-Pick C1 Antibody [NBP2-26214]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |