MKP-3: Small Molecules and Peptides
MKP-3, also called PYST1 and dual specificity phosphatase 6 (DUSP6), dephosphorylates serine, threonine, and tyrosine residues in proteins. It has a high degree of substrate selectivity for dephosphorylating ERK kinases over stress-related kinases such as p38 and JNK. MKP-3 is ubiquitinylated prior to degradation in the proteosome. The rate of MKP-3 degradation is enhanced by ERK-mediated phosphorylation.
1 result for "MKP-3 Small Molecules and Peptides" in Products
1 result for "MKP-3 Small Molecules and Peptides" in Products
MKP-3: Small Molecules and Peptides
MKP-3, also called PYST1 and dual specificity phosphatase 6 (DUSP6), dephosphorylates serine, threonine, and tyrosine residues in proteins. It has a high degree of substrate selectivity for dephosphorylating ERK kinases over stress-related kinases such as p38 and JNK. MKP-3 is ubiquitinylated prior to degradation in the proteosome. The rate of MKP-3 degradation is enhanced by ERK-mediated phosphorylation.
DUSP6 and DUSP1 inhibitor
| Chemical Name: | 3-(Cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1H-inden-1-one |
| Purity: | ≥98% (HPLC) |
