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Lymphotoxin-alpha/TNF-beta Products

TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.

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295 results for "Lymphotoxin-alpha/TNF-beta" in Products

295 results for "Lymphotoxin-alpha/TNF-beta" in Products

Lymphotoxin-alpha/TNF-beta Products

TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.

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Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Applications: ELISA
Human Luminex Cytokine Assay Standard Curves
(2)

Defined heterotrimer stoichiometry

Source: HEK293
Accession #: P01374 (rhLT alpha ), Q06643 (rhLT beta ) & Q06643 (rhLT beta )
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Assay Range: 31.2 - 2,000 pg/mL
Applications: ELISA
Human Lymphotoxin-alpha / TNF-beta ELISA Standard Curve
Source: E. coli
Accession #: P01374
Applications: BA
Recombinant Human Lymphotoxin-alpha/TNF-beta Protein Bioactivity
(2)

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB, Neut
Cytotoxicity Induced by Lymphotoxin‑ alpha/TNF‑ beta and Neutralization by Human Lymphotoxin‑ alpha/TNF‑ beta Antibody.
Applications: ELISA
Mouse Lymphotoxin-alpha/TNF-beta ELISA Kit (Colorimetric)
(2)

Biotinylated His-tag

Source: HEK293
Accession #: P01374 (alpha) & Q06643-1 (beta)
Applications: BA
Recombinant Human Lymphotoxin alpha1/beta2 Avi Protein Binding Activity
(2)
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