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3 results for "Keap1 Small Molecules and Peptides" in Products
Keap1 Small Molecules and Peptides
Keap1 is a member of the Kelch family of proteins. Keap1 contains an N-terminal BTB/POZ domain that mediates homodimerization. When dimerized, six Kelch repeats on the extended C-terminus interact with and inactivate Nrf2, a potent transcriptional activator of detoxifying enzymes, providing a homeostatic brake on oxidative stress activity.
Nrf2 signaling activator
Chemical Name:
1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole
Purity:
≥98%
Inhibitor of Keap1- Nrf2 interaction
Alternate Names:
LH601A
Chemical Name:
(1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid
Purity:
≥98%
Nrf2 inhibitor; phenotypically lethal
Chemical Name:
N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide
Purity:
≥98%
