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Jagged 1: Proteins and Enzymes
Jagged 1 is a transmembrane glycoprotein in the Delta-Serrate-Lag-2 (DSL) family of ligands that activate Notch proteins. Jagged 1 is widely expressed in adult and fetal tissues. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation. It plays a key role in vascular, hematopoietic, myogenic, and neurogenic development. Mutations in human Jagged 1 are the cause of Alagille syndrome, an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of heart, eye, vertebrae, as well as a characteristic facial appearance.
7 results for "Jagged 1 Proteins and Enzymes" in Products
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Jagged 1: Proteins and Enzymes
Jagged 1 is a transmembrane glycoprotein in the Delta-Serrate-Lag-2 (DSL) family of ligands that activate Notch proteins. Jagged 1 is widely expressed in adult and fetal tissues. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation. It plays a key role in vascular, hematopoietic, myogenic, and neurogenic development. Mutations in human Jagged 1 are the cause of Alagille syndrome, an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of heart, eye, vertebrae, as well as a characteristic facial appearance.
7 results for "Jagged 1 Proteins and Enzymes" in Products
| Source : | CHO |
| Accession # : | P78504 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | Q9QXX0.1 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | P78504 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | Q63722.2 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | Q63722 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | P78504.3 |
| Applications : | Bioactivity |
